Author(s): Remille April Cecilia P. Rocacurva, MD and Jimmy B. Catapia, MD, FPCS, FPSGS, FSOSP

Introduction:
This is a case of a 56-year-old Filipina female who presented with a four-month history of a palpable right infraclavicular lymph node that was diagnosed as metastatic melanoma on histopathology and immunohistochemical staining with no apparent primary tumor on physical examination, nasopharyngoscopy, colonoscopy and imaging studies. Patient then underwent modified radical neck dissection, right, with an unremarkable intra-operative and post-operative course. This report aimed to document the clinical profile, laboratory and imaging parameters and treatment of melanoma of unknown primary on a 65-year-old female.

Conclusion:
MUP are an uncommon subset of melanomas that present as a diagnostic challenge and are histologically and immunochemically similar with its classic counterparts with known primaries. This disease entity is managed similarly with classically occurring melanomas with nodal/metastatic disease and tend to have a more favorable outcome.

Key words: melanoma; neoplasm, unknown primary; neck dissection; Philippines

DOI: