Author(s): Johann Paulo S. Guzman MD; Marcus Lester R. Suntay, MD, FPCS and Leandro L. Resurreccion III, MD
Presented is a rare case of Wilms’ Tumor (WT) in a 3-month old female with a palpable nontender left flank mass. In the early infancy period (<6 months), there is a low incidence of malignancy in renal masses, and congenital benign renal lesions (like congenital mesoblastic nephroma) predominate in this age group. We did nephroureterectomy and lymph node sampling. Histopathology revealed localized non-metastatic COG Stage I WT with favorable histologic features. The patient underwent adjuvant chemotherapy with dactinomycin and vincristine using an institution-based protocol, which offers upfront surgery followed by chemotherapy. This approach is similar to the Children’s Oncology Group (COG) protocol.
Key words: Wilms tumor, nephrectomy, National Wilms Tumor Study